Overnight Cream vs. Clearing Serum by SkinBetter Science — What’s the Difference?

SkinBetter Science is known for its award-winning AlphaRet technology, blending a retinoid with an AHA to deliver visible results with minimal irritation. Two of their most popular products — the AlphaRet Overnight Cream and the AlphaRet Clearing Serum — may sound similar, but they’re designed for different skin concerns. Here’s a quick breakdown to help you choose the right on

AlphaRet Overnight Cream

This is the go-to for anti-ageing. It targets fine lines, wrinkles, uneven skin tone, and dullness. The formula combines AlphaRet technology with nourishing ingredients like ceramides, squalane and niacinamide to support the skin barrier and keep dryness at bay. It has a rich, creamy texture, making it ideal for normal to dry or combination skin.

Best for:

• Ageing concerns (lines, texture, pigmentation)

• Normal to dry skin types

• Those who prefer a nourishing night cream with actives

AlphaRet Clearing Serum

This serum focuses on blemish-prone and oilier skin while still offering anti-ageing benefits. It has the same AlphaRet technology, but with added salicylic acid and oil-controlling ingredients to refine pores, smooth texture and keep breakouts in check. The texture is lighter than the cream, making it perfect for those who don’t want a heavy finish.

Best for:

• Oily, combination, or breakout-prone skin

• Enlarged pores and uneven texture

• Those wanting anti-ageing + clearing benefits in one step

In Short

• Choose Overnight Cream if your main focus is anti-ageing and hydration.

• Choose Clearing Serum if your skin is oily or blemish-prone and you want smoother, clearer skin without compromising on anti-ageing benefits.

Both products are powerful, so introduce them gradually and always pair with daily SPF.